Types Of Tumor Affects The Brain - 1083 Words

Abstract: Brain is one of the vital organ in human body, it has an extensive capillary network which is highly vascularized. The brain capillary endothelial cells (BCECs), astrocytes, pericytes and neuron forms the blood brain barrier (BBB) [1]. There are several types of tumor affects the brain, one such type of tumor is Glioblastoma multiforme (GBM). GBM is the most frequent and aggressive form of primary tumor found in central nervous system, the world health organization (WHO) defined GBM as grade IV astrocytoma [2]. Therefore, this urge us to propose a novel technique to treat GBM. Carrier- Graphene oxide xxxxxxxxxxx, silica nanocapsules, xxxxxxxxxxx, drugs- Doxorubicin XXXXXXXXXXXXXX, tetrandrine XXXXXXXXXXXXXXXXX, targeting ligands – chlorotoxin, xxxxxxxx transferrin xxxxxxxxxxxx (Zeng please fill this) And then test for characterization, invitro and invivo for synthesized nanocomplex. Aim: The overall aim of this proposal is to synthesis a biocompatible nanocomplex which as an ability to pass through the BBB and specifically to treat GBM by sustained drug release. Then, to study the synergistic reinforced effect of two drugs and their resistance against fast clearance. Herein, we hypothesis, that our synthesized nanocomplex will have increased bioavailability of drugs, increased specificity for BBB and GBM, reduced drug side effects and finally, has targeted and sustained drug release. As illustrated in figure 1 the synthesized nanocomplexShow MoreRelatedEssay What are Tumors and How Can They Affect the Brain?1464 Words   |  6 Pagesdoctor found a benign, tumor within my friend’s brain at the age of thirteen, but he is now twenty-four years old and as healthy as ever. My father is the other person I know who had a tumor. A team of doctors found his tumor when he was thirty-nine years old; I was only four years old at the time. His was also benign but it was within a different spot of his brain, unfortunately he passed away twelve years after he found out he had it. What are brain tumors? Brain tumors are masses of cells thatRead MoreEpendymoma- Brain Tumor1504 Words   |  6 PagesEpendymoma is a type of brain tumor and while it is rare in adults, accounting for 2-3% of brain tumors, ependymoma is mainly found in children and accounts for around 5% of all childhood brain cancers (American Cancer Society [ACS], 2014, January 31; American Brain Tumor Association [ABTA], n.d.). The survival rate of patients with ependymoma who have survived five years after their tumor is detected is 75% Tumors occur when cells grow to excess and form a mass. While some tumors are benign, meaningRead MoreHow Does Homeostasis Affect Homeostasis1413 Words   |  6 Pages Affects on Homeostasis When biological systems tend to maintain stability while adjusting to conditions that are optimal for survival is Homeostasis. Homeostasis is kept in order by dynamic equilibrium, in which changes occur, but resists outside forces of change. However when a system is disturbed, feedback mechanisms control take action to reestablish a new balance. Homeostasis is important because by maintaining homeostasis, organisms remain healthy, strong and stable, with protection fromRead MoreRight Hemisphere And Relative Impairments1661 Words   |  7 Pageshemisphere of the brain is the â€Å"language hemisphere.† However, very few people know that the right hemisphere is also an important contributor to speech, language, and communication. Right hemisphere syndrome is a lesion in the right hemisphere of the brain that results from factors such as stokes, tumors, traumatic brain injury, or other neurological diseases (Blake, 2010). What is Stroke? Human’s body is a mechanism that constantly requires energy in order to function properly. The brain is the organRead MoreThe Effects of Tobacco on the Human Body788 Words   |  3 Pagesbronchitis. In addition, one of the problems after smoking is the inability to become pregnant. Tobacco use kills victims. (Health Effects) Tobacco is addictive and it is hard to quit. Tobacco has more than 4,000 chemicals in it. Fifty of these cause many types of cancers. Using Tobacco and being pregnant is very lethal to the infant and later the mother. Tobacco slowly kills many adults and children each day. Nursing while smoking can also cause complications to the baby and to others around. (Tobacco Facts)Read MoreSymptoms And Treatment Of Epilepsy1275 Words   |  6 PagesSeizures There are many chronic conditions that can affect people today with one such condition being epilepsy. This disease does not only affect a person physiologically but also affects how they interact with others, perform activities of daily living and the basic needs of a person, such as, driving or maintaining a job. The overall affects of this tragic and chronic disease is it can negatively affect a person’s confidence and therefore affect their basic life choices. Within this paper there willRead More The Effects of a Tumor on the Family Members Essay1261 Words   |  6 PagesThe Effects of a Tumor on the Family Members A tumor that is specifically in the frontal cortex can cause many changes physically and emotionally which can affect the way you interact with your family. Some of the functions of the frontal lobe are attention, abstract thought, problem solving, intelligence, creative thought, initiative inhibition, judgment, mood, major body movements, bowel and bladder control, memory and reasoning (retrieved from www.ect.org. What this meansRead MoreWhat Are Oncolytic Viruses?1225 Words   |  5 Pagesthe cancerous cell explodes. This releases the virus, tumor specific agents, and GM-CSF. This causes the immune system to recognize cancerous cells and fight them with the help of the virus. Who/When Was it Developed? The uses of viruses to treat cancer have been talked about since the 1900’, but only due to the recent advances in microbiology, immunology, and virology, have we been able to understand how it reduces the size of cancerous tumors. One of the earliest recorded cases of viruses killingRead MoreCell Phones And Our Health1542 Words   |  7 Pagesexpectations for social communication. People who are using their cell phones more than is necessary, it will harm their health. Cell phones make people more vulnerable of getting sick. For example, people who are addicted to their cell phones, which will affect their health, and that by touching their phone too much during the day, which can easily effect users by germs. According to the study that was made in London School of Hygiene and Tropical Medicine and Queen Mary, University of London showed thatRead MoreSymptoms And Treatment Of Cancer1528 Words   |  7 PagesINRODUCTION Oncology, a branch of science that deals with tumors and cancer, has always looked at cancer and its treatment through a biological lens. Cancer is a disease that develops when cells abnormally divide and multiply without control (Depression and Cancer). The treatment of cancer includes, but is not limited to, chemotherapy. This treatment aims to shrink tumors that result from unnecessary cells that keep dividing and multiplying. As chemotherapy only focuses on the biological treatment